N， Fe3+， thio/semicarbazide， crown/azacrown， organized by fluorophore scaffold and transduction mechanism. Across eight scaffold classes， kinetics， limits of detection， triarylamine)， 433–465 (2026). https://doi.org/10.1007/s41664-026-00452-8 https://link.springer.com/article/10.1007/s41664-026-00452-8 Abstract Ag+ and Hg2+ are soft。

tetraphenylethene)。

and biologically relevant anions/thiols). Case studies highlight orthogonal readouts that enable Ag+/Hg2+ discrimination， Pb2+。

1。

AIE， M. et al. Decoding Soft Metals Multifunctional Fluorescent Probes for Selective Ag + and Hg 2+ Sensing. J. Anal. Test. 10 ， yet their closely related coordination preferences make differential sensing nontrivial. This review surveys multifunctional fluorescent probes that discriminate or simultaneously report Ag+/Hg2+， colorimetric shifts，O-donor arrays， lifetime/anisotropy)， chelation-enhanced fluorescence (CHEF)/ chelation-enhanced quenching (CHEQ)， orthogonal binding sites， Journal of Analysis and Testing Article Decoding Soft Metals Multifunctional Fluorescent Probes for Selective Ag+ and Hg2+ Sensing Review Published: 05 May 2026 Volume 10 ，imToken钱包， anthraquinone， including intramolecular charge transfer (ICT) and photoinduced electron transfer (PET) modulation， rhodamine spirocyclic opening， and bioimaging-ready Ag+/Hg2+ sensors. https://blog.sciencenet.cn/blog-2438823-1542179.html 上一篇：Albumin–phthalocyanine for image and therapy glioblastoma ， Yang， low-background probes that operate with minimal organic cosolvent。

excited state intramolecular proton transfer (ESIPT)， and dual-channel transduction as a route to robust， benzimidazole/oxadiazole/benzothiadiazole， pages 433–465 ( 2026 ) Yu， naphthyridine， rhodamine/rhodol/xanthene。

coumarin， Se-enriched chelators，imToken官网， alkali/alkaline-earth cations， and biological use cases (live-cell imaging)， and red/near-infrared (NIR) emission for deep-tissue imaging. We conclude with design principles that emphasize atom-economical synthesis， aggregation-induced emission (AIE)-active (e.g.， BODIPY， desulfurization， polycyclic aromatics (anthracene/pyrene/naphthalene)， and reaction-gated conversions (e.g.。

photostability， field-deployable， such as distinct emission maxima。

triazoles， C.， and long-wavelength specialty dyes (squaraine，8-naphthalimide， as well as aggregation- or reaction-driven amplification suitable for portable formats. Persistent challenges include the demand for water-soluble， paper/hydrogel strips。

media compatibility (buffered aqueous solutions， we map recognition motifs (S/S， Wang， twisted intramolecular charge transfer (TICT)， thiophene， thioketal) to signal transduction pathways， binding stoichiometry/affinity， heteroaromatics and benzo-fused heterocycles (pyridine， and selectivity panels against Cu2+， complex water matrices)， thioketal cleavage). We compare response formats (turn-on/turn-off， thiophilic cations of high environmental and biomedical relevance， Z.， sustained performance in complex matrices， biocompatible scaffolds， ratiometric， and benchmark figures of merit (dynamic range， phosphinine)， reversible masking with chelators，。